DruckenThe Laboratory of Regenerative and Muscle Biology in the Department of Health Sciences and Technology at ETH Zurich is searching for a part-time animal transgenic specialist. The primary scientific interest and focus of the lab is to study the regenerative potential of stem cells, with an emphasis on pluripotent and skeletal muscle stem cells, using state-of-the-art transgenic models. The lab is seeking a highly motivated, responsible, and organized transgenic specialist to help oversee the generation of rodent transgenic animal models using CRISPR or pluripotent stem cell injections.Project backgroundThe Laboratory of Regenerative and Muscle Biology, headed by Prof. Ori Bar-Nur, is a multidisciplinary and collaborative group of scientists focused on translating basic research findings into therapeutically applicable treatments. The lab operates at the intersection of molecular and cellular biology, gene- and cell-based therapies, and tissue engineering. It extensively employs transgenesis in projects involving these research areas to advance our understanding of biological processes and to develop potential new therapies for treating muscle diseases.Job descriptionPrimary responsibilities include:
Generation of chimeric rodents from ESCs or iPSCs by blastocyst injection or morula aggregation
Generation of transgenic mice and rats by pronuclear injection, electroporation, or AAV transduction of DNA and CRISPR-Cas9 constructs
Embryo and sperm cryopreservation
In vitro fertilization and intracytoplasmic sperm injection
Reproduction-related surgical interventions (including harvesting oocytes and embryos, sperm collection, and vasectomy)
Profile
You hold at least a BSc degree in Biology, Biochemistry, Biotechnology, Bioengineering, Biomedical Sciences, or a similar research field
In addition you have working experience in a transgenic animal unit is required, as well as the ability to perform several of the responsibilities outlined in the job description
Furthermore, certification in LTK-M1 or an equivelant permit to work with lab rodents is essential.
You are an excellent communicator, collaborative, organized, and reliable
Strong communication skills and fluency in English are requiered, as the role will involve daily interactions with international PhD students and postdoctoral research fellows
WorkplaceWorkplaceWe offer
Additional training will be provided for the listed tasks
The RMB Lab is located in the SLA building on the Schwerzenbach Campus of ETH Zurich, a world-leading institute
We provide a cutting-edge work environment, multiple well-equipped facilities with expert staff, supportive colleagues, and opportunities for innovative and dynamic projects
We offer a competitive salary and benefits package. The funding and employment terms for this position adhere to the regulations of ETH Zurich
We value diversityIn line with , ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our to find out how we ensure a fair and open environment that allows everyone to grow and flourish.Curious? So are we.We look forward to receiving your online application by October 31, 2025, including the following documents: a detailed CV, a statement of experience and qualifications (no more than one page), and at least two reference letters or the names of referees. Please note that we exclusively accept applications submitted through our online application portal. Applications sent via email or postal services will not be considered.Further information about the lab can be found on our . For questions about the position, please contact Ms. Eva Skalamera at eva.skalamera@services.ethz.ch.About ETH ZürichETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.
